DDI-2010 is a yearly event providing a comprehensive update on the status of the science of drug-drug interactions and its relevance to drug development.  Presentations will be given by experts from industry and academia.  Topics covered will include literature and NDA reviews, mechanism and in vitro-in vivo extrapolation of DDI via enzyme and transporter inhibition and induction.  The conference will also include a review on the current status of DDI potential of biologics.

ETS-2010 is a bi-yearly event with emphasis on promising approaches and challenges in the accurate prediction of adverse drug effects during drug development. This year’s theme will be mechanism-based evaluation of adverse drug effects, with academic and industrial experts presenting data from in vitro, animal, and clinical studies. Topics covered will include risk factors observed in the clinic and preclinical animal species, mechanisms and mechanism-based evaluation of hepatotoxicity, as well as novel in vitro, in silico, and in vivo technologies for the accurate assessment of human adverse drug effects.